Hey Alecia
When you say lower quads I assume that you are carrying more fat in the thigh area as opposed to closer to the knee. Either way I mentioned in another post that fat located on the quadricep may be indicative of high estrogen levels, whereas fat that accumulates around the knees reflects low amounts of growth hormone. Strength coach Charles Poliquin wrote about this in an issue of Oxygen magazine a few years back if you would like to read up about it.
To correct both hormonal imbalances you can begin strength training with higher reps and shorter rest intervals, also increase your dietary intake of cruciferous vegatables like broccoli to help with the estrogen and supplement with glutimine for growth hormone.
Lastly you said your knees are knobby, what you may be referring to is knock knees or genu valgum deformaty (its not really a deformaty) either way it can be attributed to the width of your hips which increases the angle toward the knees. I dont know whether there are exercises to decrease the valgus but you should focus on increasing strength around the knees before they starts to the experience pain associated with knock knees.
Hope that helps
Teekz
